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Santarpio's operates two locations in the Boston area—one in East Boston and another in Peabody—serving New York-style pizza alongside their signature barbecue skewers. The menu centers on customizable pies with a base of Italian cheese and your choice of toppings, from the straightforward to combinations like the Works, which layers mushrooms, onions, peppers, garlic, sausage, pepperoni, extra cheese, and anchovies. Beyond pizza, the barbecue program offers lamb skewers, steak tip skewers, chicken tip skewers, and both regular and zesty lamb sausage, each served with hot cherry peppers and fresh baked Italian bread. The East Boston location sits at 111 Chelsea Street.