Palio Pizzeria sits on Main Street in Hyannis, serving wood-fired Neapolitan pizza alongside a range of Italian pastas, grinders, and panini. The menu centers on house-made components—meatballs, sausage, breadsticks, and garlic knots—while specialty pizzas span traditional options like Margherita to local interpretations such as the Cape Codder, built on a white base with shrimp, clams, and lemon. Beyond pizza, the kitchen turns out classic Italian appetizers, soups like pasta e fagioli and Italian wedding, and pasta dishes finished with house-made red sauce or pesto. The restaurant offers both indoor and outdoor seating, with online ordering, takeout, and delivery available.