Quattro occupies a corner location in Boston's North End with an unusual setup for the neighborhood: a full dining room backed by a kitchen equipped with both a custom-built rotisserie and an authentic Neapolitan brick pizza oven. The menu centers on proteins—fresh meats, seafood, pork, and poultry—cooked to order in front of diners on the rotisserie, alongside Neapolitan-style pizzas. The bar stocks wine, beer, and cordials, and the restaurant has become known for its Espresso Martini cocktails, which the website notes have sold over 750,000 units in a bottled format.