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Holyoke Pizza operates out of a straightforward storefront on South Street, offering an extensive menu built around customizable pies. The kitchen turns out both standard cheese pizzas and an ambitious roster of specialty combinations—ranging from familiar territory like Meat Lovers and Hawaiian to less common options such as Clam Casino (bacon, clams, and white sauce) and Cajun Steak. They also prepare calzones, wings, salads, and pasta dishes like Chicken Parmigiana and Eggplant Parmigiana. Gluten-free crust is available for several pizzas, including their Edie Special and Chicken Cordon Blue. The Build Your Own Pizza option lets you construct a pie to specification.